KENNEDY SPACE CENTER, Fla. (CASIS PR) – In the absence of effective countermeasures, prolonged spaceflight can result in many of the same physiological changes associated with aging—bone loss, muscle deterioration, and altered immune system function—only at a much quicker rate. This makes the microgravity environment of the International Space Station (ISS) a valuable platform for research on conditions associated with the aging process.
BOSTON, December 21, 2021 (Emulate PR) – Emulate, Inc., a leading provider of next-generation in vitro models, today announced that the Brain-Chip was sent to the International Space Station U.S. National Laboratory (ISS National Lab) to study the effects of microgravity on human brain physiology as part of the Tissue-Chips in Space initiative sponsored by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and the International Space Station National Lab (ISS-NL). The ISS provides an environment where researchers can study human health in microgravity, allowing them to isolate the effects of gravity from other factors that can impact brain cell function.
The Emulate Brain-Chip is the most comprehensive in vitro model of the human neurovascular unit, including the blood-brain barrier (BBB), for preclinical research. It contains five cell types in a dynamic and tunable microenvironment, resulting in in vivo-like gene expression and phenotypic response. Each chip is about the size of a USB thumb drive and contains two fluidic channels separated by a porous membrane. The vascular channel is lined with brain microvascular endothelial cells, while the brain channel contains cortical neurons, astrocytes, pericytes, and microglia. This allows researchers to study BBB function, the ability of drugs to cross the BBB, and the complex cell-cell interactions involved in brain physiology, disease, and drug response.
KENNEDY SPACE CENTER, Fla., December 15, 2021 (CASIS PR) – The microgravity environment on the International Space Station (ISS) has a profound impact on cells and tissues, allowing researchers to conduct life sciences research in ways not possible on the ground. SpaceX’s 24th Commercial Resupply Services (CRS) mission to the orbiting laboratory will deliver a variety of life science payloads sponsored by the ISS National Lab. From stem cell research on neurodegenerative diseases to a tissue chip experiment studying the blood-brain barrier and an investigation testing the use of bacteria to protect DNA from the stresses of spaceflight—the research launching on this mission is helping to improve the quality of life for people on Earth.
HOUSTON (NASA PR) — The 22nd SpaceX cargo resupply mission carrying scientific research and technology demonstrations launches to the International Space Station from NASA’s Kennedy Space Center in Florida no earlier than June 3. Experiments aboard include studying how water bears tolerate space, whether microgravity affects symbiotic relationships, analyzing the formation of kidney stones, and more.
Highlights of the payloads on this resupply mission include:
KENNEDY SPACE CENTER, Fla. January 14, 2021 (CASIS PR) – The Center for the Advancement of Science in Space (CASIS) has released the International Space Station (ISS) U.S. National Laboratory 2020 Annual Report. The report is intended to educate the public on ISS National Lab highlights and accomplishments from the 2020 fiscal year (October 1, 2019 through September 30, 2020).
KENNEDY SPACE CENTER, Fla., January 14, 2021 (CASIS PR) – SpaceX’s Dragon spacecraft splashed down safely off the coast of Florida last night, concluding a month-plus stay at the International Space Station (ISS) to bring back thousands of pounds of scientific research and cargo.
With this successful splashdown, SpaceX completed its 21st Commercial Resupply Services (CRS) mission to the orbiting laboratory for NASA. This also marks the first mission of the upgraded Dragon cargo spacecraft with double the powered locker capacity of previous capsules, allowing for even more research to travel back to Earth for analysis.
KENNEDY SPACE CENTER, Fla., April 7, 2020 (ISS National Lab PR) – SpaceX’s Dragon spacecraft successfully splashed down today off the coast of California, bringing back dozens of research investigations sponsored by the International Space Station (ISS) U.S. National Laboratory.
The successful splashdown and science return marks the completion of SpaceX’s 20th commercial resupply services (CRS) mission to the space station (contracted by NASA) to send critical research and supplies to the orbiting laboratory. The Dragon spacecraft spent approximately 30 days berthed to the space station before returning to Earth.